YK-11 (Capsules)

YK-11, also known as Myostine, is a nonsteroidal selective receptor modulator structurally related to dihydrotestosterone (DHT). Unlike other receptor modulators, YK-11 retains a ring structure and functions as a partial agonist at the androgen receptor [1]. The compound has been studied for its unique mechanism involving both androgen receptor activation and myostatin inhibition through follistatin upregulation, potentially providing dual anabolic signaling pathways [2]. Preclinical research in myoblast cell lines has demonstrated enhanced myogenic differentiation, myosin heavy chain expression, and myostatin antagonism. YK-11 is supplied strictly for laboratory research use in qualified facilities and is not approved for human consumption.

Chemical Structure and Identification

• Compound Name: YK-11 (Myostine)
• Per Capsule: 5 mg per capsule
• Molecular Formula: C₂₅H₃₄O₆
• Molecular Weight: 430.54 g/mol
• CAS Number: 1370003-76-1

Research Applications

• Androgen Receptor Pharmacology: Investigation of nonsteroidal mechanisms and partial agonist activity characterization [1]
• Muscle Hypertrophy Research: Preclinical studies of muscle cell differentiation, myogenic regulatory factor expression, and skeletal muscle biology [2]
• Myostatin Signaling: Mechanistic evaluation of follistatin upregulation and myostatin antagonism in muscle tissue [2]
• Osteoblast Function: Research into bone cell proliferation, mineralization, and differentiation marker expression [3]
• Comparative Androgen Receptor Studies: Cell-based assays comparing nonsteroidal AR ligand activity and selectivity [1]

Reference Citations

1. PubMed (30379415) – Studies on the in vivo metabolism of YK11: Identification and characterization of metabolites for doping controls | https://pubmed.ncbi.nlm.nih.gov/30379415/
2. Cayman Chemical/GlpBio – YK-11 Androgen Receptor Partial Agonist with Myogenic Differentiation Activity | https://pubchem.ncbi.nlm.nih.gov/
3. PubMed – YK-11 Osteoblast Differentiation and Mineralization Studies in MC3T3-E1 Cells | https://pubmed.ncbi.nlm.nih.gov/

Important Regulatory Notice

These products are for research use only and are not intended for human consumption, therapeutic use, or diagnostic purposes. All compounds described herein have not been approved by the FDA for human use. These products are strictly intended for in vitro laboratory research and analytical purposes when conducted by qualified research professionals in licensed facilities. Users are responsible for ensuring compliance with all applicable laws regarding purchase and use of these materials.