Gut Research (Capsules)

This specialized capsule formulation features a blend of three research peptides and compounds tailored for gastrointestinal tract research. BPC-157, a pentadecapeptide from human gastric juice, and KPV, a tripeptide fragment of alpha-melanocyte-stimulating hormone, are known for their protective and signaling properties. Additionally, PEA, an endogenous lipid mediator, is included for its role in immune modulation. Together, these components are intended for in-depth research on intestinal barrier function and inflammatory response mechanisms in controlled laboratory environments.

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This specialized capsule formulation combines three research peptides and compounds designed for gastrointestinal tract research applications. BPC-157 is a pentadecapeptide originally isolated from human gastric juice, known for its pleiotropic cytoprotective effects in preclinical models [1]. KPV (Lys-Pro-Val) is the C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone, characterized for its anti-inflammatory signaling properties [2]. PEA (palmitoylethanolamide) is an endogenous lipid mediator studied for immune and inflammatory modulation. Together, these compounds are designed for research examining intestinal barrier function, mucosal protection, and inflammatory response mechanisms in controlled laboratory settings.

Chemical Structure and Identification

BPC-157

  • Compound Name: BPC-157 (Gastric Pentadecapeptide)
  • Per Capsule: 500 mcg per capsule
  • Molecular Formula: C₆₂H₉₈N₁₆O₂₂
  • Molecular Weight: 1419.56 g/mol
  • CAS Number: 137525-51-0

KPV

  • Compound Name: KPV (Lys-Pro-Val)
  • Per Capsule: 500 mcg per capsule
  • Molecular Formula: C₁₆H₃₀N₄O₄
  • Molecular Weight: 342.43 g/mol
  • CAS Number: 67727-97-3

PEA

  • Compound Name: Palmitoylethanolamide
  • Per Capsule: 400 mcg per capsule
  • Molecular Formula: C₁₈H₃₇NO₂
  • Molecular Weight: 299.49 g/mol
  • CAS Number: 544-31-0

Research Applications

  • Gastrointestinal Mucosal Integrity: Preclinical evaluation of BPC-157’s effects on mucosal protection and barrier function maintenance [1]
  • Inflammatory Bowel Response: Mechanistic studies examining tissue damage and inflammatory responses using multiple complementary compounds [3]
  • Anti-inflammatory Signaling Pathways: KPV research into melanocortin receptor signaling and NF-kappaB pathway modulation [2]
  • Wound Healing Research: Investigation of angiogenesis, fibroblast activity, and tissue repair mechanisms in gastrointestinal models [1]
  • Immune Modulation: Comparative studies of immune cell function and cytokine production under inflammatory conditions [4]

Reference Citations

  1. PubMed (40756949) – Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review | https://pubmed.ncbi.nlm.nih.gov/40756949/
  2. Gastroenterology (2007) – PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation | https://pubmed.ncbi.nlm.nih.gov/
  3. PMC/PMC12446177 – Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing | https://pmc.ncbi.nlm.nih.gov/articles/PMC12446177/
  4. PubMed (12851308) – New insights into the functions of alpha-MSH and related peptides in the immune system | https://pubmed.ncbi.nlm.nih.gov/12851308/
  5. PMC/PMC2095288 – Alpha-MSH Related Peptides: A New Class of Anti-inflammatory and Immunomodulating Drugs | https://pmc.ncbi.nlm.nih.gov/articles/PMC2095288/

Important Regulatory Notice

These products are for research use only and are not intended for human consumption, therapeutic use, or diagnostic purposes. All compounds described herein have not been approved by the FDA for human use. These products are strictly intended for in vitro laboratory research and analytical purposes when conducted by qualified research professionals in licensed facilities. Users are responsible for ensuring compliance with all applicable laws regarding purchase and use of these materials.

Important Regulatory Notice

These products are for research use only and are not intended for human consumption, therapeutic use, or diagnostic purposes. All compounds described herein have not been approved by the FDA for human use. These products are strictly intended for in vitro laboratory research and analytical purposes when conducted by qualified research professionals in licensed facilities. Users are responsible for ensuring compliance with all applicable laws regarding purchase and use of these materials.