Acetic Acid Solution

Acetic acid solution is a weak organic acid (ethanoic acid) formulation prepared as a sterile, non-pyrogenic solution specifically engineered for laboratory research applications requiring a mild acidic environment for peptide and protein reconstitution. Pure acetic acid (glacial acetic acid, 100%) is a colorless volatile liquid with a characteristic pungent vinegar-like odor, possessing strong solvent properties for polar and non-polar compounds. For research applications, acetic acid is typically supplied as a dilute aqueous solution (commonly 0.6% v/v) that maintains chemical reactivity while providing improved handling safety, reduced volatility, and enhanced stability compared to pure glacial acetic acid. The dilute formulation provides optimal pH adjustments for protein and peptide dissolution without causing denaturation or precipitation, making it ideal for reconstituting lyophilized research compounds and preparing experimental solutions. Acetic acid functions through multiple mechanisms in research contexts: proton donor in acid-base chemistry, weak acid buffer system formation, organic synthesis reactions, chromatographic solvent system component, and protein stabilization agent preventing aggregation. The 10mL multi-use research-grade vial is supplied as a sterile, measured solution suitable for controlled laboratory environments, formulated for compatibility with peptides, proteins, growth factors, and other sensitive compounds used in bench research.

Chemical Structure and Identification

• Molecular Formula: C₂H₄O₂
• Molecular Weight: 60.05 g/mol
• CAS Number: 64-19-7

Research Applications

• Peptide and Protein Reconstitution: Mild acidic solvent for dissolving lyophilized research compounds without denaturation [1]
• pH Adjustment and Buffer Preparation: Weak acid component in acetate buffer systems for maintaining pH stability [2]
• Chromatographic Mobile Phase: HPLC and liquid chromatography solvent system component for peptide and protein separation [2]
• Organic Synthesis: Reagent for esterification, acetylation, and other synthetic transformations in laboratory settings [3]
• Protein Stability and Aggregation Prevention: Acidic environment preventing unwanted precipitation and maintaining solubility in cell culture [1]
• Research Solution Formulation: Compatible vehicle for preparing experimental preparations in controlled laboratory settings [2]

Reference Citations

1. Acetic Acid 0.6% Solution for peptide reconstitution – Oasis Labs | https://myoasislabs.com/product/acetic-acid/
2. Acetic acid analytical and HPLC applications | https://www.sigmaaldrich.com/US/en/product/saj/010310
3. Acetic acid chemical properties and synthesis applications | https://www.chemicalbook.com/ChemicalProductProperty_EN_CB7854064.htm
4. Acetic acid solutions in analytical chemistry – VWR/Avantor | https://www.avantorsciences.com/us/en/product/8927229/acetic-acid-10-v-v-in-aqueous-solution-1-9

Important Regulatory Notice

These products are for research use only and are not intended for human consumption, therapeutic use, or diagnostic purposes. All compounds described herein have not been approved by the FDA for human use. These products are strictly intended for in vitro laboratory research and analytical purposes when conducted by qualified research professionals in licensed facilities. Users are responsible for ensuring compliance with all applicable laws regarding purchase and use of these materials.